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Are you seeking a pharmaceutical ingredient that offers unparalleled versatility and effectiveness? Look no further than PHARCOGOL PEG (Polyethylene Glycol).

Optimize your pharmaceutical products with PEG. For further information on how PEG can revolutionize your formulations, reach out to our experienced team of experts.

Innovation

We have been developing innovative solutions for several decades and our innovation is evidenced in our quest for increased processing efficiency, in-depth support for quality requirements, and tailored supply chain solutions. You can depend on us for the science, technology and know how that you need to support your own ability to innovate.

Versatility

The versatility of PEGs has been proven over decades of use in pharmaceuticals. As Active laxative and colonic lavage formulations. They are used widely as excipients in solid oral dosage forms, ointments and creams, capsules and liquid medications, and suppositories. Versatility is further enhanced by multiple product forms including liquid, powder, granular and flake materials.

Consistency

With PEGs, we can help you find the ideal product for your application. PEGs are available in a wide range of viscosities and melting points for formulating flexibility. By choosing a suitable product grade, or blending products, you can achieve the desired balance of water solubility, hygroscopicity, vapour pressure, melting or freezing range, and viscosity on a regular basis.

Products

Polyethylene Glycols Compliance

PEGs comply with the stringent regulatory requirements for pharmaceutical applications. They conform to the US Pharmacopeia / National Formulary (USP/NF) monographs for polyethylene glycols. Selected liquid and solid PEGs are compliant with the European Pharmacopoeia (Ph. Eur.) requirements for Macrogols. Product Quality is in line with cGMP on a World-Scale Production Platform. The manufacturing, handling and storage of all PEGs are conducted with all appropriate current Good Manufacturing Practice (cGMP) in our world-scale production facilities. Our ability to supply PEGs meeting appropriate global regulatory requirements globally is supported by our inventory management solutions and a network of strategically located terminal facilities.

Polyethylene Glycols

A Leading Choice for Pharmaceuticals

Polyethylene Glycols (PEGs) are highly versatile excipients and Active Pharmaceutical Ingredients (API) produced to meet the exacting requirements of the Pharmaceutical Industry but PEGs do more than just meet requirements as they establish industry standards for innovation, versatility, consistency and compliance.

PEGs Chemistry and Product Line

PEGs are water soluble linear polymers formed by the addition reaction of ethylene oxide to an ethylene glycol equivalent. The general formula for polyethylene glycol is: H–(OCH2CH2)n–OH where “n” is the average number of repeating oxyethylene groups.

PEGs are available in a wide range of molecular weights to offer flexibility to help optimize formulations. Depending on molecular weight, products are available in liquid, solid, granular, powder, and flake forms.

PEGs are available in average molecular weights ranging from 300 to 8000. Low aldehyde grades of PEG 300, 400, and 600 are available.

Pharcogol (Polyethylene Glycol) Grades

Product
Trade Name
Form
Polyethylene Glycol 200
Pharcogol 200
Liquid
Polyethylene Glycol 300
Pharcogol 300
Liquid
Polyethylene Glycol 400
Pharcogol 400
Liquid
Polyethylene Glycol 600
Pharcogol 600
Liquid
Polyethylene Glycol 800
Pharcogol 800
Liquid
Polyethylene Glycol 1500
Pharcogol 1500
Semi-Solid
Polyethylene Glycol 3350
Pharcogol 3350
Granules, Powder, Flakes
Polyethylene Glycol 3400
Pharcogol 3400
Granules, Powder, Flakes
Polyethylene Glycol 4000
Pharcogol 4000
Granules, Powder, Flakes
Polyethylene Glycol 6000
Pharcogol 6000
Granules, Powder, Flakes
Polyethylene Glycol 8000
Pharcogol 8000
Granules, Powder, Flakes

Pharcogol (Polyethylene Glycol) Applications

Pharmaceuticals

Application
Description
Recommended Products
Actives
Laxatives and Colonic Lavage
PEGs are well-known in the treatment of chronic constipation. Functioning as an osmotic laxative, they can provide a mild and effective treatment without common side effects seen in other laxative types. They are also widely used as colonic lavage to facilitate bowel cleansing prior to medical procedures such as colonoscopies, radiological exams, or gastrointestinal surgery
PEG 3350 & 4000
Tablet Binding or Coating
PEGS act as binders and fillers offering internal and external lubrication. They are also effective plasticizers in tablet coating formulations, providing good hardness, water solubility and lubricity.
PEG 6000 & 8000
Excipients
Gelatin Capsules
Products are used extensively in soft gelatin capsules. They enhance solubility of the active substance as the primary water-soluble component in the liquid fill. For hard gelatin capsules, products effectively solubilize active ingredients in a melt-fill protocol. A suitable antioxidant additive such as Butylated Hydroxytoluene (BHT) may be beneficial in providing oxidative stability to the active ingredient and to the PEG under filling conditions.
All Grades
Liquid Medications
PEGS are ingredients in liquid oral-dose medications such as cough medicines and elixirs. where they function as solubilizers and non-alcohol diluents. Other applications include nose and ear drops and spray-on medicines.
LIQUID PEGs
Suppositories
PEGs serve as a formulation base to dissolve the active substance. They also allow enhanced bioavailability by facilitating effective and complete release of the active substance in the body. High molecular weight PEGs are also used to coat suppositories, providing elasticity and lubricity
PEG 400 & PEG 600
Chemical Intermediates
PEGs are used in the synthesis of pharmaceutical actives such as diesters, carbonates, carbamates, and PEG/protein conjugates (PEGylation).
All Grades
Chemical Processing Aids
PEGs have been in pharmaceutical granulation technology for decades. PEGS can offer control to achieve a more uniform particle size distribution, reduce fines concentration, enhance tablet hardness, and add lubricity.
PEG 1500 & PEG 8000