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PEG 400 (Polyethylene Glycol 400 | Macrogol 400)

Pharcogol 400

PHARCOGOL 400 is a low molecular weight polyethylene glycol with excellent solubilizing properties. It serves as an effective solvent for poorly water-soluble drugs, plasticizer for film coatings, and humectant in topical formulations. Completely miscible with water and many organic solvents.

Compliance:

USP-NFEPBP

Quick Information

Product Line:
Pharmaceutical
Category:
PEG
Grade:
PEG 400
CAS Number:
25322-68-3

Key Applications

  • Solvent
  • Plasticizer
  • Humectant

Pharma Grade PEG 400: Leading Manufacturer, Supplier & Exporter in India

Pharcos Speciality Ltd, based in India, is a trusted manufacturer, exporter and supplier of Pharmaceutical Grade Polyethylene Glycol 400 (PEG 400, CAS No. 25322-68-3). With a focus on quality and compliance, we serve pharmaceutical companies, bulk buyers, wholesale buyers, dealers and distributors globally. Our PEG 400 adheres to stringent pharmacopeial standards, including USP-NF, EP and BP, making it an essential ingredient in pharmaceutical formulations worldwide.

Polyethylene Glycol 400: Product Overview

PEG 400 is a low molecular weight polyethylene glycol known for its superior solubilizing properties, making it an ideal solvent for poorly water-soluble drugs. It plays a critical role in enhancing drug solubility, thereby improving bioavailability and overall efficacy. It is commonly used in pharmaceutical formulations to ensure that drugs are delivered effectively and safely to patients. Its high purity and excellent miscibility with water and many organic solvents make it indispensable for various pharmaceutical applications.

PEG 400 in Pharmaceutical Applications

  • Solvent for Poorly Water-Soluble Drugs: PEG 400 is widely used as a solvent to dissolve poorly water-soluble drugs, enabling their effective incorporation into pharmaceutical formulations such as oral tablets and injectables.
  • Plasticizer for Film Coatings: It is also utilized as a plasticizer in film coatings for tablets and capsules, improving their flexibility, appearance and overall stability.
  • Humectant in Topical Formulations: PEG 400 acts as a humectant in pharmaceutical creams and ointments, helping to retain moisture and prevent dehydration, thereby ensuring optimal hydration for the skin.

Macrogol 400: Commitment to R&D and Continuous Innovation

At Pharcos Speciality Ltd, we are dedicated to the continuous improvement of our products. Our in-house research and development team works relentlessly to innovate and optimize the use of PEG 400 in the pharmaceutical industry. By constantly upgrading our manufacturing processes, we ensure that our products meet the highest standards of quality, safety and performance, keeping up with the evolving needs of the pharmaceutical sector.

All Pharcogol® (PEG) products are manufactured in strict conformance with internationally recognized pharmacopeial standards, including the United States Pharmacopeia / National Formulary (USP/NF), European Pharmacopoeia (Ph. Eur. / EP), British Pharmacopoeia (BP), Indian Pharmacopoeia (IP), Japanese Pharmacopoeia (JP), and other major compendial references. Ph. Eur., EP, and BP are interchangeable designations commonly used to refer to European and British pharmacopeial standards, and our products comply with all applicable monographs thereunder.

For customers with specific regulatory or market requirements, we are fully equipped to supply products conforming to any additional pharmacopeial standard upon request. Please contact our technical team to discuss your compliance requirements.

Applications
Industries Served
Frequently Asked Questions

Technical Information

Common questions about PEG 400 (Polyethylene Glycol 400 | Macrogol 400)

What are the primary pharmaceutical applications of PEG 400?

PEG 400 is used as a solvent for poorly water-soluble drugs, a plasticizer for film coatings and a humectant in topical formulations.

Do PEG 400 compliant with pharmacopeial standards?

Yes, PEG 400 meets the required USP-NF, EP and BP standards, ensuring its suitability for pharmaceutical applications.

How does PEG 400 improve drug delivery?

PEG 400 enhances the solubility of poorly water-soluble drugs, which improves their bioavailability and allows for more effective drug delivery.

Why PEG 400 be used in oral pharmaceuticals?

Yes, PEG 400 is commonly used in oral formulations as a solvent to dissolve active ingredients and facilitate their absorption.

What makes PEG 400 suitable for topical formulations?

PEG 400 is used as a humectant in topical products, helping to maintain moisture and prevent skin dehydration in creams and ointments.

How does Pharcos Speciality Ltd ensure the quality of PEG 400?

We adhere to strict quality control procedures and conduct regular testing to ensure that our PEG 400 meets all pharmacopeial requirements.

Why PEG 400 safe for pharmaceutical use?

Yes, when used according to established guidelines, PEG 400 is considered safe for use in pharmaceutical formulations.

What sets Pharcos Speciality Ltd apart from other suppliers?

Our focus on continuous R&D, product innovation and strict compliance with global pharmacopeial standards ensures that our PEG 400 meets the highest quality benchmarks.

Why PEG 400 be used in injectable drug formulations?

Yes, PEG 400 is used in injectable formulations as a solvent, ensuring effective drug delivery through parenteral routes.

How is PEG 400 manufactured?

Our PEG 400 is produced under stringent quality control and manufacturing practices, ensuring consistency, safety and compliance with all regulatory requirements.

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